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Eur J Heart Fail 24(12):22382250 Borlaug BA (2020) Evaluation and management of heart failure with preserved ejection fraction

GLP-1 Activity GLP-1 receptor activation can help reduce appetite, slow gastric emptying, support insulin response, and improve blood sugar regulation

Agents such as semaglutide and tirzepatide have demonstrated especially notable efficacy in this regard, further reinforcing the concept that targeted weight management can meaningfully influence cardiovascular outcomes

16,17,18,19 As new indications continue to be developed, GLP-1 drugs demonstrate immense potential in the medical field, with future research expected to expand their therapeutic applications

I wont again review here the issues of exorbitant costs, reimbursement coverage by insurers, health inequities, and lack of availability, since these were previously summarized