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"Tirzepatide, a Dual GIP/GLP-1 Receptor Co-agonist for the Treatment of Type 2 Diabetes with Unmatched Effectiveness Regrading Glycaemic Control and Body Weight Reduction." Cardiovascular Diabetology, 2022, 21:169
doi: 10.1001/jama.2016.0287 [DOI] [PMC free article] [PubMed] [Google Scholar]
This middle region is specifically recognized by ECL1, ECL2, and the extracellular tip of TM1, all of which exhibit receptor-specific conformation and structural flexibility (Fig
Knudsen LB, Nielsen PF, Huusfeldt PO, et al
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