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They work through completely different mechanisms
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Medications prescribed included, metformin extended release 80% (n=32), topiramate 32.5% (n=13), bupropion 32.5% (n=13), phentermine 20% (n=8), and naltrexone 2.5% (n=1)

All statistical analyses were performed with SAS software, version 9.4 TS1M5 (SAS Institute)