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When to take the medications While there are no direct interactions between Wegovy and the flu jab, a bit of planning around when to take the medications can reduce the impact of side effects: Best time to get vaccinated: Any time youre feeling well whilst on Wegovy Earlier in the flu season (October-November) for best protection On a day when you can rest afterwards if needed You might want to wait if: Youre experiencing severe Wegovy side effects (wait until they settle) Youre severely nauseated or vomiting You have a fever or acute illness (standard vaccine guidance) Theres no need to skip your Wegovy dose when getting the flu jab