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for Zepbound, evaluate after 3 months at maintenance dose with a target of 5% weight loss
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Courrges J-P, Vilsbll T, Zdravkovic M, et al

Furthermore, pharmacological inhibition of autophagy suppresses Sirt3 activity, resulting in S accumulation and enhanced autosis, an autophagy-dependent form of cell death (He et al., 2022)
