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However, the data presented here in conjunction with clinical data on this mechanism in ALS suggests that it may not be of value to perform clinical studies with GLP-1 agonists in ALS and that resources may be more usefully focussed elsewhere
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Common strategies for extending the duration of GLP-1 RAs include: Amino Acid Sequence Optimization : Reducing rapid degradation by DPP-4 enzymes to extend the drug's half-life
pmid:21177976 48
IBS-M (mixed) alternating diarrhoea and constipation episodes
10.1534/genetics.118.300985 68 MurataY.WhartonR
