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Skipping doses or administering too much too soon can lead to unwanted side effects or reduced effectiveness

The FDA has not flagged this combination as contraindicated, and real-world patient data from millions of people using both medications simultaneously confirms their safety profile together

Furthermore, short-acting GLP-1RAs predominantly affect postprandial glucose levels, mainly by reducing gastric emptying speed, while long-acting GLP-1RAs more strongly affect fasting glucose levels through a combination of increased fasting insulin and reduced hepatic gluconeogenesis [14]

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May 27, 2022
