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Each group of BV2 cell supernatants was collected, and the LDH concentration was determined using an LDH assay kit (Nanjing KeyGen Biotech Co., Ltd.) according to the manufacturer's instructions

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"Effects of retatrutide on body composition in people with type 2 diabetes: a substudy of a phase 2, double-blind, parallel-group, placebo-controlled, randomised trial." The Lancet Diabetes & Endocrinology

They found increased expression of TNF- in the taste epithelium, as well as altered expression of TNF- receptors 1 and 2

Current medical guidelines from ACOG and medication manufacturers advise against use