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The New York Times Magazine

Ozempic, Wegovy) have gained prominence for their efficacy in managing type 2 diabetes and aiding weight loss

Although there have been no specific trials to show cardiorenal benefit for GLP-1RA or SGLT2i when used as first-line therapy or as monotherapy or in newly diagnosed T2D, the benefit seen in the CV outcome trials has not been found to vary with the duration of diabetes, suggesting that similar benefits might be seen early in the course of disease.4 The benefits are also not dependent on the presence of metformin

While gastrointestinal adverse effects exist, they generally do not lead to higher hospitalization rates due to disease flares (99)

If your healthcare provider prescribes a GLP-1 for weight loss, they must prescribe the FDA-approved version for weight loss