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The Semaglutide Treatment Effect on Body Weight (STEP) trials demonstrated sustained benefits over 68 weeks, with patients maintaining 15% to 18% weight loss on continuous therapy

Thats where I see these drugs fitting in. For the foreseeable future, thats going to be a little bit of a difficult question to answer

As mentioned earlier, this is not fat loss it's water loss

Week 16 and Beyond: Reaching Maintenance By week 16, you may have lost 15-20 pounds or more, depending on your starting weight