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Description
Tirzepatide demonstrated remarkable weight-reducing efficacy in randomized controlled trials such as SURMOUNT-1 and SURMOUNT-2, with mean body-weight reductions ranging from 15 to 22.5% (32, 33)

Additional common side effects in children are fever and gastroenteritis

Tirzepatide is administered subcutaneously once weekly at doses ranging from 2.5 mg to 15 mg, with gradual dose escalation recommended to minimize gastrointestinal adverse effects

administered retatrutide in doses up to 8 mg for a total of 48 weeks in patients with a BMI 30 kg/m 2 or with a BMI of 2730 kg/m 2 and a coexisting weight-related condition [39]

Behav Brain Res (2017) 327:6574
