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Excessive production of O 2 and its derivatives contributes to damage in cellular components such as lipid peroxidation, protein carbonylation, and DNA oxidation, thereby triggering inflammation and promoting disease progression [126]
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The lancet
Notably, DNA oxidation products such as 8-OHdG have been found at elevated levels in MASLD patients and have shown a correlation with disease severity [101, 121, 122]
[DOI] [PubMed] [Google Scholar] 113.Jensen SBK, Janus C, Lundgren JR, et al
