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Mechanisms controlling glucose-induced GLP-1 secretion in human small intestine

By fusing GLP-1 with fatty acids for acylation, the molecular self-association is promoted, thus prolonging the diffusion time of the drug from the injection site

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21 Headache outcomes may show more benefit over a longer trial duration, as during the relatively short time horizon of this trial other factors may also have contributed to headache such as medication overuse and opiate use, which occur in approximately one-third of IIH patients

Hegeds ZI, Jakab ME, Gergely TG, Sayour NV, Kovcs A, Antal S, et al