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You can read the full paper in Nature here: #Genetics #PrecisionMedicine #GLP1 #Obesity #Biotech #Semaglutide #Tirzepatide #Nature #23andMe #GWAS #ClinicalResearch | 24 comments on LinkedIn

While evidence supports some protective mechanisms, clinical efficacy remains modest in human trials

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The mice received thioacetamide (TAA) (150 mg/kg, biweekly) via intraperitoneal (i.p.) injection for nine consecutive weeks to induce liver fibrosis

For eligible and willing patients, bariatric surgery, which provides sustained benefits, may be the best option from a clinical and economic perspective