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Some people lose significant thigh fat during GLP-1 treatment, particularly those on higher doses of tirzepatide or retatrutide , which can reduce the suitability of this site over time

GLP-1s would be part of the solution but not the solution

Anyone exploring a metabolic peptide during a surplus should also note their fasted glucose if they have a meter, since improving readings are part of the mechanism this whole strategy hopes to engage

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