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The condition causes higher levels of androgen hormone production, resulting in symptoms such as irregular menstrual cycles, acne, excess hair growth, cysts, skin tags, thinning hair, skin darkening, and infertility

He also thinks trials should look at strategies to mitigate lean mass loss, and examine sex-specific responses, since GLP-1 medications are hormonal in nature and can impact people in different ways

These studies demonstrate that the serum leptin levels vary in different sex, age and body mass index (BMI) [197], [198], [199], [200], [201], [202]
