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[DOI] [PMC free article] [PubMed] [Google Scholar] 7.Tang ST, Tang HQ, Su H, et al

When statins first launched they were ~$8000/year (not too far off GLP1s)

The surge reflects its incredible effectiveness

According to the FDA prescribing information, these gastrointestinal symptoms are dose-dependent and represent the primary reason for treatment discontinuation in clinical trials

Recently, an -cell GLP-1r KO mouse was generated by crossing a loxP flanked humanized GLP-1r mouse with a Gcg -Cre mouse (251)
