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Clinical trials have shown that patients using tirzepatide achieved greater reductions in blood sugar compared to those using other medications

Although the direct mode of action of dietary fibre via the GM remains to be shown, these trials underscore the potential importance of including GM modulation strategies as part of diabetes intervention trials, especially for the production of beneficial metabolites such as SCFAs [205]

Patients may develop a parkinsonian gait, characterized by a forward-leaning posture and taking small but quick steps, which also increases fall risk

FIGURE 1 Acinar and ductal pancreatic cells, as well as cells from other organs, may also serve as targets for reprogramming

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