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In reviewing the content of the claims in this batch of warning letters, most of the concerning language on online websites advertising these products that was flagged by the FDA is unsurprising, including: Named the brand product as a comparative reference or therapeutic equivalent Stated the compounded product was a generic of the brand product Included efficacy claims for the compounded product Used the words FDA-approved in the advertising copy But some of the language that was flagged by the FDA was less direct, with the FDAs expressed concern being that the advertising may have given the impression of FDA approval

That $149 ongoing rate is one of the lowest weve seen for compounded semaglutide

Honigberg et al., 2020

For patients with heart failure taking beta-blockers, optimization of beta-blocker dosing should be prioritized to maintain target heart rate goals in accordance with heart failure guidelines

However, athletes may benefit from a slower titration schedule that preserves energy availability for training