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If nausea persists beyond 8 weeks at the same dose, discuss whether a slower titration or alternative medication would be better

The SURMOUNT clinical program demonstrated substantial weight reductions establishing tirzepatide as one of the most effective obesity medications available

Many plans also require: Prior authorization Documentation of medical necessity Records of previous weight-management efforts Ongoing monitoring by a healthcare provider Some plans may require step therapy, meaning lower-cost treatments must be tried before Wegovy is approved

There is also a broader innovation risk

Our findings underscore the possibility for wider applications for these medications but also highlight important risks that should be carefully monitored in people taking these drugs.