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Early clinical data suggests tirzepatide produces slightly greater weight loss and metabolic improvements in certain populations compared to semaglutide alone

Tang H, et al

If blood sugar remains uncontrolled after 4 weeks on 0.5 mg, increase to: 1 mg SC once a week

Liraglutide has also been found to protect against LDL-induced endothelial hyperpermeability by influencing the expression of the cellular junction protein Occludin and thus maintaining vascular permeability

Risk of thyroid cancer related to glucagon-like peptide-1 receptor agonists: a systematic review with meta-analysis of harms of randomized controlled trials
