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Low-dose semaglutide reduced alcohol craving and consumption in adults with alcohol use disorder.
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Specifically, the study fixed 12 conserved residues from known GLP-1RAs and used ProteinMPNN to generate 10,000 novel sequences

Semaglutide can lower blood pressure in some patients, but individual responses vary significantly based on metabolic factors, baseline cardiovascular status, and genetic predispositions
