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Conversely, Minneapolis-St
Microinjection of exendin-4 into the NTS reduces intake of palatable high-fat diet and inhibits food reward behavior [716], and hindbrain inhibition of GLP-1R via administration of exendin (939) into the 4th ventricle increases food intake [717]

GLP-1 RAs are considered to have a lower administration burden

Como a substncia ainda est em fase de investigao, seu perfil completo de segurana e suas contraindicaes no foram totalmente estabelecidos

PMID 3543057
