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Today, GLP-1 drugs improve blood sugar control and promote weight loss, transforming metabolic disease management

For advantages beyond glycemic management, research has shown that it can aid weight loss by modulating signals that affect food intake

Orforglipron is in Phase 3 clinical trials now

Semaglutide is primarily metabolized via proteolytic cleavage of the peptide backbone by DPP4 and neutral endopeptidases and sequential beta-oxidation of the fatty di-acid side chain

We compared 24,221 type 2 diabetic patients prescribed semaglutide, 49,266 patients prescribed liraglutide, and 45,153 patients prescribed dulaglutide to 551,119 type 2 diabetic patients prescribed insulin to determine whether there were differences in the risk of thyroid cancer in each group