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While it does not directly cause nutrient loss, it often leads people to reduce fiber intake further, which compounds the problem of inadequate nutrition

Tirzepatide acts on GLP-1 and GIP pathways that influence insulin response, digestion, and appetite

The question is whether retatrutide glucagon component provides a specific, direct benefit to liver fat metabolism beyond what weight loss alone would produce

First, treatment allocation was not randomized, raising the potential for residual confounding despite extensive pretreatment covariate adjustment through propensity score matching

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