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Ice or heat therapy, gentle stretching, and low-impact physical activity also address pain mechanisms without systemic drug interactions

oi:10.1038/ijo.2016.121 The Vagus Nerve at the Interface of the Microbiota-Gut-Brain Axis

The anti-diabetic property of curcumin is due to the induction of glucagon-like peptide-1 (GLP-1) secretion in intestinal L-cells 7,8,9
