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In people with normal glucose tolerance, the early (30- or 60-minute) rise in plasma glucose following a 75 g oral glucose challenge is directly proportional to the rate of emptying, while this relationship is reversed at 120 minutes (the time point conventionally used in the diagnosis of diabetes)

Conversely, most NENs lack GLP-1R and should be unaffected by these agents

ORahilly, Stephen (2021-04)

Effect of the Glucagon-Like peptide-1 receptor agonists semaglutide and liraglutide on kidney outcomes in patients with Type 2 Diabetes: pooled analysis of SUSTAIN 6 and LEADER

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