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Changing Your Reward Pathways Addictive substances cause unnatural spikes in dopamine

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73 Hydration: Dehydration is a common, often overlooked cause of fatigue

GLP-1 medications are generally safe to combine with most common medications, though certain interactions require monitoringparticularly diabetes medications that may need dose adjustment

However, semaglutide exerted broader effects, extending laterally and more deeply into the posterior ARH compared to liraglutide, potentially explaining its greater effectiveness in weight reduction (147)