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Although GLP-1 receptor agonists (GLP-1RAs) were initially developed for the management of diabetes and weight loss, their therapeutic applications have since broadened considerably to encompass a range of cardiovascular, renal, and metabolic disorders [15,16,17]

Hypothyroidism, that contributes to the reduction of the basal metabolic rate [10], can be primitive or depend on hypothalamic-pituitary dysfunction

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Importantly, diabetes remission rates were higher in participants who had undergone BPD-DS, RYGB or sleeve gastrectomy compared with the standard of care [21]

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