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Interestingly, the previously observed positive contrast effect was spared in S2, with a weaker residual effect specifically on the consumption of the more palatable pellet type

Dietary factors : Low-fibre diets are associated with increased risk, though recent research suggests the relationship is more complex than previously thought

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Residues from M371 ECL3 to G377 ECL3 have been mutated to Ala (with A376 to Gly), showing only a modest effect upon GLP-1 pharmacology (Dods and Donnelly, 2015)