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Description
In LEAD-2 and LEAD-5, investigators reported that SBP reductions occurred prior to substantial weight loss and may not have been fully explained by changes in body weight
Others may actually improve with weight loss
Furthermore, through the activation of canonical G-protein coupled receptors, GLP-1 receptors activate adenylyl cyclase which leads to an increased production of cAMP, a second messenger involved in vasodilation [27]

Started dieting at age 10
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Mechanism of Action The dual action of Mounjaro is what sets it apart from other medications
