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Treatment should only continue if there is a reduction in HbA1c of at least 11 mmol/mol (1.0%) and weight loss of at least 3% of initial body weight after 6 months

Lynnette Rodgers is a PhD nursing student at the University of Texas Medical Branch in Galveston and a medical liaison at Novo Nordisk Inc., Plainsboro, New Jersey

Recent advances in peptide-based therapies for obesity and type 2 diabetes

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In line with this notion, pharmacologic or genetic suppression of GLP-1R in the lateral septum attenuates the ability of cocaine to activate the mesolimbic dopamine system, as assessed by hyperactivity, reward in the CPP test, and dopamine enhancement in the NAc (Harasta et al., 2015