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13 , 23 , 24 , 25 , 26 , 27 , 28 , 29 Furthermore, Phase 1 mechanism of action studies of tirzepatide, a dual GIP and GLP1 receptor agonist, approved for the treatment of type 2 diabetes and obesity, have shown reductions in weight
By studying the animals in metabolic cages that measure metabolic rate, it was further explored that, despite the GLP-1-MK-801-treated mice being significantly smaller in size and consuming less food than the obese control group, they burned the same amount of calories

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Muscle loss (which starts in your 30s and accelerates in midlife) reduces your bodys ability to efficiently burn energy and maintain strength

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