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Long-term trials like LEADER confirmed cardiovascular and renal safety for liraglutide in T2D, with no increased risk of pancreatitis or thyroid malignancy [34]
These parameters were also measured at the end-of-trial visit at week 111 (within 5 days before or after the scheduled visit day)
A dietitian or health coach can help identify these drift patterns before they entrench
This is why blanket advice falls flat
Indeed, an early formulation of a DPP-4 inhibitor improved oral glucose tolerance in GLP-1R knockout mice and in GIP receptor knockout mice [15]
