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semaglutide flu like symptoms Side Effects: What to Expect in the First Weeks Flu-Like Symptoms on GLP-1: Causes
Description
The STEP 1 trial (Wilding et al., The Lancet, 2021) showed an average weight loss of 14.9% over 68 weeks versus 2.4% in the placebo group a landmark result that established semaglutide as the benchmark for GLP-1 weight loss

Symptomology timeline concerns Symptoms of diabetes develop slowly over many years

Circulation, 2005, Vol 112(17), pp 27352752

These program mechanics directly influence payer-level changes, which is why the next subsection summarizes expected Medicare and Medicaid timelines and their implications for broader coverage
& Culotti, J
