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& Auwerx, J
They often report cold intolerance, fatigue, poor hair quality and feeling "crap"
We used these methods in both mice with complete GLP-1R knockout (GLP-1R KO) and wild-type C57BL/6N (WT) mice
Phase 3 TRIUMPH-4 demonstrated 28.7% mean weight loss at 68 weeks with the 12 mg dose, confirming the exceptional Phase 2 results (24.2% at 48 weeks
J Hepatol 2012;56:952-964
