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Future studies comparing the effect of GLP-1RA treatment according to the presence of T2DM are required to define optimal indications

5,13,14 Loss of muscle leads to reductions in strength and balance, increasing the risk of fatigue, lower bone density, and injury

Last reviewed: May 21, 2026 Last updated: May 21, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

How GLP-1 affects weight loss The GLP-1 hormone affects weight management in several ways

Check-ins at 4, 8, and 12 weeks off medication give you early data to make an informed decision about whether to restart
