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Crucially, several of these effects appear independent of weight loss, strengthening the argument that GLP-1s promote direct neurobiological benefits for brain health and dementia prevention

The semaglutide dosage calculator and peptide calculator on SeekPeptides can help researchers determine appropriate dosing for their specific protocols

The dosage

The baseline cystatin Cbased eGFR (eGFRcys) and creatinine-based eGFR (eGFRcre) values of the participants were 35.3 ml/min/1.73 m 2 and 36.0 ml/min/1.73 m 2 , respectively

Optional additions include green tea extract (EGCG 300-500mg daily) for modest additional metabolic support and fiber supplements if dietary fiber intake falls short of 25-35 grams daily