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Keep a backup gel pack in the freezer

These concerns are especially real for patients managing chronic conditions or those seeking sustainable, long-term weight loss rather than rapid changes

Step 8: Withdraw the needle and release the skin pinch

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Given the strong female predominance of AITD and the midlife rise in metabolic risk during the menopausal transition, targeted trials in perimenopausal and postmenopausal women are warranted, with attention to hormone status, body-composition change, cardiovascular risk, and dose adjustments of thyroid medications during weight loss [1,2,66] (Figure 2)