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GLP-1 activation suppresses appetite and slows gastric emptying

The New England journal of medicine , 389 (12), 10691084

293 Interleukin-1 receptor-associated kinase 1/4 (IRAK1/4) is the main kinase in the TLR-mediated pathway, and inhibition of IRAK1/4 can block the TLR4/NF-B pathway and reduce intestinal inflammation

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Individual response factors may influence treatment outcomes