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Es el primer frmaco desde Saxenda (aprobado en 2014) que ofrece un impacto significativo sobre la obesidad

The thyroid safety concern stems from preclinical research in rodents, where semaglutide caused dose-dependent and treatment-duration-dependent thyroid C-cell tumors, including medullary thyroid carcinoma (MTC)

Here, the framework suggests cautious re-evaluation focused on assay standardization, context-specific endpoints, and direct pharmacologic modulation rather than continued reliance on observational correlations

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If approved, would be first amylin/GLP-1 combination treatment