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Hansen DV, Hanson JE, Sheng M

It works in the brain to reduce your appetite

Research-grade retatrutide typically costs $120-180 for a 5 mg vial, $200-300 for 10 mg, and $350-500 for 20 mg

Lixisenatide: Gastrointestinal: acute pancreatitis, hemorrhagic and necrotizing pancreatitis, ileus, intestinal obstruction, severe constipation including fecal impaction Hepatobiliary: cholecystitis, cholelithiasis requiring cholecystectomy Neurologic: dysgeusia, dysesthesia Pulmonary: pulmonary aspiration has occurred in patients receiving GLP-1 receptor agonists under-going elective surgeries or procedures requiring general anesthesia or deep sedation

Athletes who time GLP-1 therapy around their competitive calendar consistently report better outcomes than those who start mid-season and fight the medication's mechanism throughout their training cycle