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Zepbound Active and Inactive Ingredients The active ingredient in Zepbound is tirzepatide

Another novel glucose-lowering agent is tirzepatide which has a dual mechanism of action: a GLP-1 and a glucose-dependent insulinotropic polypeptide (GIP) co-agonist

Semaglutide (Ozempic and Wegovy) resulted in a 14.9% reduction in body weight in clinical trials, while tirzepatide (Mounjaro and Zepbound) led to a 20.9% body weight reduction

More research is necessary to understand whether effects on inflammation or glycemic control account for this

Risk of nonarteritic anterior ischemic optic neuropathy in patients prescribed semaglutide