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Retatrutide has shown the highest weight loss numbers in trials so far (28.7% in Phase 3 TRIUMPH-4 vs 22.5% for tirzepatide in SURMOUNT-1 and 15.8% for semaglutide in STEP-1)

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While weight reduction has long been a primary goal of incretin-based therapies, emerging data suggest that metabolic improvements Read More Oral GLP-1 Therapy in 2026: Will Easier Administration Change When We Start Treatment