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Diabetes GLP-1s perform better but still leak demand: Diabetes-indicated GLP-1s show higher retention (24% at one year) and face fewer access hurdles due to broader coverage and disease framing, yet 76% of demand remains unmet

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Weight loss plateaus are common during GLP-1 therapy, but they don't mean failure

Combining orlistat with Wegovy represents a multi-mechanism approach to weight management, but understanding drug interactions and individual response patterns is essential before starting dual therapy