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Description
The trial enrolled 9,650 adults aged 50 years or older diagnosed with T2D and glycated hemoglobin (HbA1c) between 6.5% and 10.0%

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That choice of scaffold is significant: the GIP backbone provides the structural framework for high-affinity GIP receptor engagement, while targeted substitutions were introduced so the same chain retains meaningful activity at the GLP-1 receptor
