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They are mainly used for moderate to severe UC unresponsive to anti-TNF alpha agents (patients failed at least one or more TNF inhibitors before)

It is especially important to seek professional medical care if your depression symptoms are severe enough to affect your daily life

Additional safety considerations include tirzepatide's boxed warning for thyroid C-cell tumors, risk of pancreatitis (symptoms include severe persistent abdominal pain, sometimes radiating to the back), gallbladder disease, and potential complications in patients with diabetic retinopathy

52 JingY.YuY.BaiF.WangL.YangD.ZhangC.et al (2021b)
