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Anhedonia is not currently a formally established or quantified side effect in the same way as nausea, vomiting, diarrhoea and constipation

Given that both GIP receptor agonism and antagonism have only been thoroughly investigated in combination with GLP-1 receptor agonism, long-term clinical studies of GIP receptor antagonism alone are needed to evaluate the adverse effect profile

Gastrointestinal issues : such as diarrhea, constipation and gassiness Headache Stomach issues : including nausea, vomiting, pain or distension (bloat) Semaglutide Safety Semaglutide Safety Semaglutide, when prescribed and monitored by healthcare professionals, is generally regarded as safe
