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Originally developed as a diabetes medication, semaglutide is also FDA-approved for weight loss

Major incretins such as GLP-1 and GIP can control appetite by reducing feelings of hunger and by increasing satiety and have a regulatory effect on glucose homeostasis through the reduction of blood glucose levels and insulin release ( Figure 1 ) ( Figure 1 Although previous studies have demonstrated that GLP-1 has positive effects on attenuating neuropathology, its function and specific actions in CNS diseases have not been reviewed comprehensively

Food and Drug Administration (FDA) approved Ozempic to treat type 2 diabetes

On average, people who took semaglutide lost 15.8% of their weight

Instruct patients to contact their physician if cholelithiasis or cholecystitis is suspected for appropriate clinical follow-up [see Warnings and Precautions (5.8)]