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However, gastrointestinal side effects, such as nausea and vomiting, often challenge long-term adherence

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The balanced triple-agonist profile is hypothesized to combine glycemic control (GLP-1/GIP) with increased energy expenditure (glucagon) in metabolic research models

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The treatment dependent changes in glycemia did not lead to a different proportion of subjects moving from the prediabetic condition to a normal glycemia after the intervention